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5-fluorouracil-loaded poly(D,L-lactide-co-glycolide) nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

aqueous solution

Type Complex Compound
Formula
Role core
2

5-fluoro-2,4(1H,3H)pyrimidinedione

5-fluorouracil 5-Fluorouracil fluorouracil Adrucil® adrucil Efudex® efudex 5-FU 5-Fu 5FU
Type Single Compound
Formula CONHCONHCHCF
Role loaded material
3

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Characterization

Method Source
scanning electron microscopy

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Biological effects

Biological system Test details Source
BALB/c mouse with hepatocellular carcinoma HCC-LM3-fLuc cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 5-fluoro-2,4(1H,3H)pyrimidinedione
  • poly(lactic-co-glycolic acid)
  • water
  1. RbOoIK59oqHTbostLxvONEQlWd4MHY0
  2. L2djvvlPqR
Product

5-fluorouracil-loaded poly(D,L-lactide-co-glycolide) nanoparticles

References

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