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curcumin-loaded methoxypoly(ethylene glycol)-poly(lactic acid)-poly(β-amino ester) micelles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic acid)-poly(β-amino ester)

PLA-PAE
Type Polymer
Formula
Role core
2

mPEG

Type Polymer
Formula
Role layer
3

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione

1,7-bis(4-hydroxy-3-methoxy phenyl)-1,6-heptadiene-3,5-diene 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione keto form curcumin diferuloylmethane curcumin CCM CUM CUR Cum Cur CM CU Cm
Type Single Compound
Formula C21H20O6
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
HT-29 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

curcumin-loaded methoxypoly(ethylene glycol)-poly(lactic acid)-poly(β-amino ester) micelles

Hydrodynamic diameter: 139.6 - 166.4 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Product

curcumin-loaded methoxypoly(ethylene glycol)-poly(lactic acid)-poly(β-amino ester) micelles

Hydrodynamic diameter: 149.1 - 183.1 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
  • methoxypoly(ethylene glycol)-poly(lactic acid)-poly(β-amino ester)
  1. IJSkxhh
Product

curcumin-loaded methoxypoly(ethylene glycol)-poly(lactic acid)-poly(β-amino ester) micelles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
  • methoxypoly(ethylene glycol)-poly(lactic acid)-poly(β-amino ester)
  1. Es1W5N0
Product

curcumin-loaded methoxypoly(ethylene glycol)-poly(lactic acid)-poly(β-amino ester) micelles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Product

curcumin-loaded methoxypoly(ethylene glycol)-poly(lactic acid)-poly(β-amino ester) micelles

Hydrodynamic diameter: 158.3 - 183.7 nm

Medium: water

Support: none

References

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