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CPP-Dox conjugate-encapsulated NGR-targeted DPPC/MSPC/DSPE-PEG2000 liposomes

Based on

1 Articles
2014 Most recent source

Composition

1

HEPES buffer

Type Complex Compound
Formula
Role core
2

CPP peptide-doxorubicin conjugate

CPP-Dox conjugate
Type Biomolecule
Formula
Role loaded material
3

1,2-dipalmitoyl-sn-glycero-phosphatidylcholine

dipalmitoyl phosphatidylcholine dipalmitoylphosphatidylcholine DPPC
Type Single Compound
Formula C40H80NO8P
Role layer
4

1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine

monostearoylphosphatidylcholine MSPC
Type Single Compound
Formula C26H54NO7P
Role loaded material
5

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-maleimide(polyethylene glycol)

DSPE-PEG2000-Mal
Type Polymer
Formula
Role loaded material
6

NGR peptide

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
female Nu/Nu nude mouse bearing HT-1080 xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. tkXXxo7A84RgR
  2. dDlcl
  3. jNpYtXJjMgru2sPgrf5xfPmyqUl
Product

CPP-Dox conjugate-encapsulated NGR-targeted DPPC/MSPC/DSPE-PEG2000 liposomes

Size: not specified

Medium: modified Eagle's medium with fetal bovine serum

Support: none

Method 2

Type: Physical formation
Source:
  1. cDuwxwE6m0W6RyL
Product

CPP-Dox conjugate-encapsulated NGR-targeted DPPC/MSPC/DSPE-PEG2000 liposomes

Diameter: 88.82 - 89.64 nm

Medium: water

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-maleimide(polyethylene glycol)
  1. qnOoGhdQzHYy
Product

CPP-Dox conjugate-encapsulated NGR-targeted DPPC/MSPC/DSPE-PEG2000 liposomes

Size: not specified

Medium/Support: none

References

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