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DOX-loaded 4sPCLDEAS micelles

Based on

1 Articles
2014 Most recent source

Composition

1

four arm star-shaped poly(ε-caprolactone)-b-poly((N,N-diethylaminoethyl methacrylate)-r-(N-(3-sulfopropyl)-N-methacryloxyethyl-N,N-diethylammonium betaine))

4sPCLDEAS
Type Polymer
Formula
Role raw materials
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
atomic force microscopy

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Biological effects

Biological system Test details Source
human epithelial carcinoma HeLa cell spheroids

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • four arm star-shaped poly(ε-caprolactone)-b-poly((N,N-diethylaminoethyl methacrylate)-r-(N-(3-sulfopropyl)-N-methacryloxyethyl-N,N-diethylammonium betaine))
  • adriblastin
Product

DOX-loaded 4sPCLDEAS micelles

Method 2

Type: Physical formation
Source:
Starting materials
  • adriblastin
  • four arm star-shaped poly(ε-caprolactone)-b-poly((N,N-diethylaminoethyl methacrylate)-r-(N-(3-sulfopropyl)-N-methacryloxyethyl-N,N-diethylammonium betaine))
Product

DOX-loaded 4sPCLDEAS micelles

Method 3

Type: Physical formation
Source:
Starting materials
  • adriblastin
  • four arm star-shaped poly(ε-caprolactone)-b-poly((N,N-diethylaminoethyl methacrylate)-r-(N-(3-sulfopropyl)-N-methacryloxyethyl-N,N-diethylammonium betaine))
Product

DOX-loaded 4sPCLDEAS micelles

Method 4

Type: Physical formation
Source:
Starting materials
  • adriblastin
  • four arm star-shaped poly(ε-caprolactone)-b-poly((N,N-diethylaminoethyl methacrylate)-r-(N-(3-sulfopropyl)-N-methacryloxyethyl-N,N-diethylammonium betaine))
Product

DOX-loaded 4sPCLDEAS micelles

Method 5

Type: Physical formation
Source:
Starting materials
  • four arm star-shaped poly(ε-caprolactone)-b-poly((N,N-diethylaminoethyl methacrylate)-r-(N-(3-sulfopropyl)-N-methacryloxyethyl-N,N-diethylammonium betaine))
  • adriblastin
Product

DOX-loaded 4sPCLDEAS micelles

References

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