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navitoclax-loaded EPC/chol/DSPE-PEG2000 nanoliposomes

Based on

1 Articles
2016 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

EPC/DSPE-PEG2000

Type Complex Compound
Formula
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
4

4-(4-{[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-N-[(4-{[(2R)-4-(4-morpholinyl)-1-(phenylsulfanyl)-2-butanyl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide

navitoclax
Type Single Compound
Formula C47H55ClF3N5O6S3
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • [polyethyleneglycol]2000-n-1,2-distearoyl-sn-glycero-3-phosphothanolammine
  • egg phosphatidylcholine
See all (4)
  1. JjDlBRmQMDnYKNNtIUd
  2. qBbUO9ZCT3n8GGQH
  3. 5twx5
Product

navitoclax-loaded EPC/chol/DSPE-PEG2000 nanoliposomes

Hydrodynamic diameter: 82.60 - 94.32 nm

Medium/Support: none

References

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