Fast insight into nanotechnology

Access easily searchable nanoscience data, synthesis methods and literature

irinotecan hydrochloride-loaded polymer-lipid-coated mesoporous silica nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role core
2

irinotecan hydrochloride

camptosar CPT-11
Type Single Compound
Formula C33H39ClN4O6
Role loaded material
3

DOPCDSPC mixture

Type Complex Compound
Formula
Role layer
4

Pluronic P123-DOPE

P123-DOPE
Type Polymer
Formula
Role layer
5

Pluronic P123-DSPE

P123-DSPE
Type Polymer
Formula
Role layer

Properties

Applications

Area Application Source
medicine/veterinary

More information available to subscribers only.

Or, view sample content

Characterization

Method Source
transmission electron microscopy

More information available to subscribers only.

Or, view sample content

Biological effects

Biological system Test details Source
BALB/c nude mouse bearing MCF-7/BCRP drug resistant xenograft tumor

More information available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  • Pluronic P123-DOPE
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
See all (5)
  1. ZMFy71PEt5
Product

irinotecan hydrochloride-loaded polymer-lipid-coated mesoporous silica nanoparticles

References

Full content is available to subscribers only

To view content please choose from the following:

We use cookies to improve your experience with our site. More information

Sign up for a free trial