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CPT/PLGA-loaded silica nanocapsules

Based on

1 Articles
2014 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role layer
3

O-(succinylaminoethyl)-O'-methylpolyethylene glycol 2000

Type Polymer
Formula
Role layer
4

(S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione

1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione (S)-(+)-camptothecin camptothecin CPT CMT CP
Type Single Compound
Formula C20H16N2O4
Role loaded material
5

(3-aminopropyl)-triethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety 3-aminopropyltriethoxysilane moiety γ-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role dopant

Properties

Applications

Characterization

Method Source
transmission electron microscopy

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Biological effects

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • silicic acid tetraethyl ester
  • ammonia aqueous solution
  • water
See all (5)
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Product

CPT/PLGA-loaded silica nanocapsules

References

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