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iSur-pDNA and siVEGF-loaded TC nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

trimethyl chitosan-cysteine conjugate

TC conjugate TC
Type Biomolecule
Formula
Role raw materials
2

Survivin shRNA-expression pDNA

iSur-pDNA
Type Biomolecule
Formula
Role loaded material
3

vascular endothelial growth factor small interfering RNA

VEGF siRNA siVEGF
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability dependent on media

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human colon adenocarcinoma Caco-2 cell and human Burkitt's lymphoma (Raji B) cell co-cultured monolayer

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • trimethyl chitosan-cysteine conjugate
  • vascular endothelial growth factor small interfering RNA
  • Survivin shRNA-expression pDNA
  1. ICGrsXFKBugaYB3Xu9cbeeVDkvfq36
  2. xHGD
Product

iSur-pDNA and siVEGF-loaded TC nanoparticles

Hydrodynamic diameter: 137.0 - 154.2 nm

Medium/Support: none

References

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