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FITC-pDNA and TAMRA-siRNA-loaded GTC nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

galactose-modified trimethyl chitosan-cysteine conjugate

GTC conjugate GTC
Type Biomolecule
Formula
Role raw materials
2

FITC-labeled Survivin shRNA-expression pDNA

FITC-labeled iSur-pDNA FITC-iSur-pDNA
Type Biomolecule
Formula
Role loaded material
3

TAMRA-labeled siRNA

TAMRA-siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
glutathione-responsive pDNA release dependent on glutathione concentration

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Applications

Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
human colon adenocarcinoma Caco-2 cell and human Burkitt's lymphoma (Raji B) cell co-cultured monolayer

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • TAMRA-labeled siRNA
  • galactose-modified trimethyl chitosan-cysteine conjugate
  • FITC-labeled Survivin shRNA-expression pDNA
  1. aXRSxg0XnvRk8iguEyv6neoGtWMtos
  2. Qy7b
Product

FITC-pDNA and TAMRA-siRNA-loaded GTC nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • TAMRA-labeled siRNA
  • galactose-modified trimethyl chitosan-cysteine conjugate
  • FITC-labeled Survivin shRNA-expression pDNA
  1. 95y3dtBJG7nd6APUeqyOk1KiyNuyPs
  2. pSZn
Product

FITC-pDNA and TAMRA-siRNA-loaded GTC nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • TAMRA-labeled siRNA
  • galactose-modified trimethyl chitosan-cysteine conjugate
  • FITC-labeled Survivin shRNA-expression pDNA
  1. 8wgPy8JCqfCr35aV79fMwbKulXQpni
  2. wXzc
Product

FITC-pDNA and TAMRA-siRNA-loaded GTC nanoparticles

Size: not specified

Medium/Support: none

References

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