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doxorubicin-loaded PEG-PAMAM-gold nanorods

Based on

1 Articles
2014 Most recent source

Composition

1

CTAB-gold nanorods

CTAB-AuNR
Type Nano Material
Formula
Role core
2

16-mercapto-hexadecanoic acid

16-mercaptohexadecanoic acid mercaptohexadecanoic acid 16-mercaptopalmitic acid 16-MHDA silole 16-MP MHDA MHA
Type Single Compound
Formula HS(CH2)15COOH
Role layer
3

PEG-PAMAM dendrimer

Type Nano Material
Formula
Role layer
4

Traut's reagent moiety

Traut's reagent moiety
Type Single Compound
Formula -C4H8NS
Role layer
5

maleimide-modified doxorubicin

Mal-DOX
Type Single Compound
Formula C37H42N4O13
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse xenografted with mouse colon carcinoma 26 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. 8dCWYWuQeuFfWq9X
  2. iOCfjg5k
Product

doxorubicin-loaded PEG-PAMAM-gold nanorods

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

doxorubicin-loaded PEG-PAMAM-gold nanorods

Diameter: 76.17 nm

Medium: phosphate buffer solution

Support: none

References

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