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CPP-Dox conjugate-encapsulated DPPC/MSPC/DSPE-PEG2000 liposomes

Based on

1 Articles
2014 Most recent source

Composition

1

HEPES buffer

Type Complex Compound
Formula
Role core
2

CPP peptide-doxorubicin conjugate

CPP-Dox conjugate
Type Biomolecule
Formula
Role loaded material
3

1,2-dipalmitoyl-sn-glycero-phosphatidylcholine

dipalmitoyl phosphatidylcholine dipalmitoylphosphatidylcholine DPPC
Type Single Compound
Formula C40H80NO8P
Role layer
4

1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine

monostearoylphosphatidylcholine MSPC
Type Single Compound
Formula C26H54NO7P
Role loaded material
5

1,2-distearyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

DSPE-PEG2000
Type Polymer
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
female Nu/Nu nude mouse bearing HT-1080 xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
  • 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine
  • 1,2-distearyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. 3YjpjkXV5QBGRvOIK39kK
Product

CPP-Dox conjugate-encapsulated DPPC/MSPC/DSPE-PEG2000 liposomes

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. fjH37GC3XbEkv
  2. TnyoZ
  3. t5bp4hTlvLssaeOwswJFuivGUTp
Product

CPP-Dox conjugate-encapsulated DPPC/MSPC/DSPE-PEG2000 liposomes

Size: not specified

Medium: modified Eagle's medium with fetal bovine serum

Support: none

Method 3

Type: Physical formation
Source:
  1. IAaE6B7tETg6giV
Product

CPP-Dox conjugate-encapsulated DPPC/MSPC/DSPE-PEG2000 liposomes

Diameter: 86.57 - 88.79 nm

Medium: water

Support: none

References

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