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doxorubicin-loaded poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

Based on

1 Articles
2016 Most recent source

Composition

1

poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

mPEG-b-(PCL-g-P(DA30-co-DMAEMA10)) micelles mPEG-b-(PCL-g-P(DA-co-DMAEMA)) micelles
Type Nano Material
Formula
Role carriers
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on pH

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Applications

Area Application Source
drug delivery

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
4T1 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • adriblastin
  • poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate)
  1. jGlVpvkYWpzzHkbrFd6BZiW68YJy
Product

doxorubicin-loaded poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

Method 2

Type: Physical formation
Source:
Starting materials
  • adriblastin
  • poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate)
  1. DM51Y2vJKHrl5sWudi0jRzSherIS
Product

doxorubicin-loaded poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

Method 3

Type: Physical formation
Source:
Starting materials
  • adriblastin
  • poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate)
  1. J0zkgvWraSbixmFH6fNZf4IVprvH
Product

doxorubicin-loaded poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

References

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