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high density lipoprotein mimicking peptide phospholipid nanoscaffold with NIR-fluorescent core nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

cholesteryl oleate

CO
Type Single Compound
Formula C43H74O2
Role core
2

1,1'-dioctadecyl-3,3,3',3'-tetramethylindotricarbocyanine iodide bis-oleate

fluorescent dye DiR-BOA DiR-BOA
Type Single Compound
Formula C61H93N2Br
Role loaded material
3

(2R)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate

1,2-dimyristoyl-sn-glycero-3-phosphocholine dimyristoyl-2-hydroxy-sn-glycero-3-phosphocholine 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine 1,2-dinonadecanoyl-sn-glycero-3-phosphocholine 1,2-dimyristoyl-sn-glycero-3- phosphocholine 1,2-dimyristoyl-sn-glycero-3-phosphocholine 2-dimyristoyl-sn-glycero-3-phosphocholine dimyristoyl-sn-glycero-3-phosphocholine L-α-dimyristoylphosphatidylcholine dimyristoyl phosphatidylcholine dimyristoylphosphatidylcholine di-14:0PC DMPC DMPE
Type Single Compound
Formula C36H72NO8P
Role layer
4

ApoA-1 mimetic peptide

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • (2R)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
  • cholesteryl oleate
  • 1,1'-dioctadecyl-3,3,3',3'-tetramethylindotricarbocyanine iodide bis-oleate
  1. 07h8vS1AKqFEhReYbEdbf
Product

high density lipoprotein mimicking peptide phospholipid nanoscaffold with NIR-fluorescent core nanoparticles

Hydrodynamic diameter: 16.7 - 18.5 nm

Medium/Support: none

References

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