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5-fluorouracil-loaded 1-(β-L-ribofuranosyl)-5-amino-pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

1-(β-L-ribofuranosyl)-5-amino-pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione

Type Single Compound
Formula C11H13N5O6
Role raw materials
2

5-fluoro-2,4(1H,3H)pyrimidinedione

5-Fluorouracil 5-fluorouracil fluorouracil Adrucil® Efudex® adrucil efudex 5-FU 5-Fu 5FU
Type Single Compound
Formula C4H3FN2O2
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
drug delivery

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Characterization

Method Source
fluorescence spectroscopy dependent on temperature

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Biological effects

Biological system Test details Source
female BALB/c athymic nude mouse bearing HSC-3 oral squamous cell carcinoma

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1-(β-L-ribofuranosyl)-5-amino-pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione
  1. T3cDreTARZicjnB1nDdDMou5p
Product

5-fluorouracil-loaded 1-(β-L-ribofuranosyl)-5-amino-pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione nanoparticles

References

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