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doxorubicin and siRNA-loaded polyethylene glycol-poly(N-(2,2';-dithiobis(ethylamine)) aspartamide)-poly(2-(diisopropyl amino)ethyl methacrylate) triblock copolymer micelles

Based on

1 Articles
2014 Most recent source

Composition

1

polyethylene glycol-poly(N-(2,2';-dithiobis(ethylamine)) aspartamide)-poly(2-(diisopropyl amino)ethyl methacrylate) triblock copolymer micelles

PEG-PAsp(AED)-PDPA micelles polymer micelles
Type Nano Material
Formula
Role raw materials
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
3

siRNA

Type Complex Compound
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on glutathione adding

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
human ovarian cancer SKOV-3 cells

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Preparation

Method 1

Type: Physical formation
Source:
  1. I9XfaOCuAvs0i8W
  2. E48KU8qsgg6uzQYP
  3. 5JPNmZ
Product

doxorubicin and siRNA-loaded polyethylene glycol-poly(N-(2,2';-dithiobis(ethylamine)) aspartamide)-poly(2-(diisopropyl amino)ethyl methacrylate) triblock copolymer micelles

References

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