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doxorubicin-loaded mPEG-Cy-PCL nanomicelles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role core
2

methoxy poly(ethylene glycol)-amine-heptamethylcyanine dye-poly(ε-caprolactone)

methoxy poly(ethylene glycol)-cyanine-poly(ε-caprolactone) mPEG5k-Cy-PCL10k mPEG-Cy-PCL
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on with and without laser irradiation

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse with human uterine cervix carcinoma HeLa cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • doxorubicin
  • methoxy poly(ethylene glycol)-amine-heptamethylcyanine dye-poly(ε-caprolactone)
  1. fZEJ22YLEPA5yAVY
  2. mBYMpOBza3Pkg2
Product

doxorubicin-loaded mPEG-Cy-PCL nanomicelles

Hydrodynamic diameter: ~ 80 - 200 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • doxorubicin
  • methoxy poly(ethylene glycol)-amine-heptamethylcyanine dye-poly(ε-caprolactone)
  1. iXpbXfJXlahfNi1a
  2. RzCBntf8xSO5Fq
Product

doxorubicin-loaded mPEG-Cy-PCL nanomicelles

Hydrodynamic diameter: 125.10 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • doxorubicin
  • methoxy poly(ethylene glycol)-amine-heptamethylcyanine dye-poly(ε-caprolactone)
  1. 0IeFiMfzmr7JRlfG
  2. 5ChoHMgMobxzFS
Product

doxorubicin-loaded mPEG-Cy-PCL nanomicelles

Hydrodynamic diameter: 153.47 nm

Medium/Support: none

References

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