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PEG-conjugated cis-aconitic anhydride anhydride-functionalized doxorubicin micelles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PEG-conjugated cis-aconitic anhydride-functionalized doxorubicin

CAD-PEG-CAD
Type Polymer
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse with mouse hepatoma H22 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • PEG-conjugated cis-aconitic anhydride-functionalized doxorubicin
  • phosphate buffer solution
Product

PEG-conjugated cis-aconitic anhydride anhydride-functionalized doxorubicin micelles

Hydrodynamic radius: 45 - 59 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • PEG-conjugated cis-aconitic anhydride-functionalized doxorubicin
  • phosphate buffer solution
Product

PEG-conjugated cis-aconitic anhydride anhydride-functionalized doxorubicin micelles

Hydrodynamic radius: 39.7 - 57.3 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • PEG-conjugated cis-aconitic anhydride-functionalized doxorubicin
  • phosphate buffer solution
Product

PEG-conjugated cis-aconitic anhydride anhydride-functionalized doxorubicin micelles

Hydrodynamic radius: 47 - 71 nm

Medium: phosphate buffer solution

Support: none

Method 4

Type: Physical formation
Source:
Product

PEG-conjugated cis-aconitic anhydride anhydride-functionalized doxorubicin micelles

Diameter: ~ 80 nm

Medium/Support: none

References

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