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lipid-coated iodinated cisplatin nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

cis-diaminediiodoplatinum

iodinated cisplatin CDDP-I
Type Single Compound
Formula H6I2N2Pt
Role loaded material
3

1,2-dioleoyl-sn-glycero-3-phosphate

dioleoyl phosphatidic acid dioleoylphosphatidic acid DOPA
Type Single Compound
Formula C39H73O8P
Role layer
4

1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane chloride

N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane chloride 1,2-dioleoyl-3-trimethyl-ammonium-propane (chloride salt) (1,2-dioleoyloxypropyl)-N,N,N-trimethylammonium chloride 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) 1,2-dioleoyl-3-trimethylammonium-propane chloride salt 1,2-dioleoyl-3-trimethylammoniumpropane chloride salt 1,2-dioleoyloxy-3-trimethylammonium-propane chloride 1,2-dioleoyl-3-trimethyl-ammonium-propane chloride (2,3-dioleoyloxypropyl)trimethylammonium chloride 1,2-dioleoyl-3-(trimethylammonio)propane chloride 1,2-dioleoyl-3-trimethylammonium-propane chloride 2,3-dioleoyloxy-propyl-trimethylammonium chloride 1,2-di-O-octadecenyl-3-trimethylammonium-propane 1,2-dioleoyl-3-trimethylammoniumpropane chloride dioleoyltrimethyl-ammoniumpropane chloride DOTAP (chloride salt) DOTAP chloride DOTAP DOTMA
Type Single Compound
Formula C42H80ClNO4
Role layer
5

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
6

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) 2000

DSPE-PEG-2000
Type Polymer
Formula
Role loaded material
7

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) 2000

DSPE-PEG 2000 DSPE-PEG-AA
Type Polymer
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on media

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
melanoma 1205Lu cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

lipid-coated iodinated cisplatin nanoparticles

Hydrodynamic diameter: 40 - 45 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • cis-diamminediaquoplatinum(II) dinitrate
  • water
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Product

lipid-coated iodinated cisplatin nanoparticles

Diameter: 30 - 40 nm

Medium/Support: none

References

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