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doxorubicin-paclitaxel-loaded mPEG-b-PLG-b-PLL/DOCA nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

deoxycholated methoxy poly(ethylene glycol)-b-poly(L-glutamic acid)-b-poly(L-lysine)

mPEG-b-PLG-b-PLL/DOCA
Type Polymer
Formula
Role carriers
2

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
3

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Source
doxorubicin release dependent on pH

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
lung cancer A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • deoxycholated methoxy poly(ethylene glycol)-b-poly(L-glutamic acid)-b-poly(L-lysine)
  • adriblastin
  • Paclitaxel
  1. UzVp
Product

doxorubicin-paclitaxel-loaded mPEG-b-PLG-b-PLL/DOCA nanoparticles

References

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