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doxorubicin-loaded folic acid-loaded 3-aminopropyltriethoxysilane/γ-3-mercaptopropyl triethoxysilane-modified mesoporous silica nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

mesoporous silica

Type Nano Material
Formula
Role core
2

(3-mercaptopropyl)-triethoxysilane

γ-3-mercaptopropyl triethoxysilane (3-mercaptopropyl)triethoxysilane 3-(mercaptopropyl)triethoxysilane 3-(triethoxysilyl)-1-propanethiol 3-mercaptopropyl triethoxysilane γ-mercaptopropyl triethoxysilane 3-mercaptopropyltriethoxysilane 3-Mercaptopropyltriethoxysilane mercaptopropyltriethoxysilane silane-SH 3-MPTES MPTES MPTS MPMS
Type Single Compound
Formula C9H22O3SSi
Role partial layer
3

(3-aminopropyl)trimethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety γ-aminopropyltriethoxysilane moiety 3-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role graft
4

folate acid

folic acid folate FOL FA
Type Single Compound
Formula C19H19N7O6
Role graft
5

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on pH

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
HeLa cell line

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. KI9SqpeJxSR4ufyGA8IScyucNqw94zDiRp
  2. Yg0fhz8C
  3. d5wC
Product

doxorubicin-loaded folic acid-loaded 3-aminopropyltriethoxysilane/γ-3-mercaptopropyl triethoxysilane-modified mesoporous silica nanoparticles

References

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