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monomeric RGD-modified lipid liposomes

Based on

1 Articles
2014 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

egg phosphatidylcholine

EPC
Type Complex Compound
Formula
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
4

3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one

3-(2-benzothiazolyl)-N,N-diethylumbelliferylamine 3-(2-benzothiazolyl)-7-(diethylamino)coumarin 6-coumarin coumarin 6 coumarin-6 C6 dye Cou6 C-6
Type Single Compound
Formula C20H18N2O2S
Role loaded material
5

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) 2000

DSPE-PEG 2000
Type Polymer
Formula
Role layer
6

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)-N-succinimide

DSPE-PEG-NHS
Type Polymer
Formula
Role layer
7

arginine-glycine-aspartic acid-D-phenylalanine-lysine cyclic peptide

cyclic (Arg-Gly-Asp-D-Phe-Lys(mpa)) peptide Arg-Gly-Asp-D-Phe-Lys cyclic pentapeptide Arg-Gly-Asp-DPhe-Lys cyclic pentapeptide cyclo(Arg-Gly-Asp-D-Phe-Lys) cyclic(RGDfK) c(RGDfK) cRGDfK RGDfK moRGD RGD
Type Single Compound
Formula C27H41N9O7
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
B16 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

monomeric RGD-modified lipid liposomes

Size: not specified

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • arginine-glycine-aspartic acid-D-phenylalanine-lysine cyclic peptide
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)-N-succinimide
  1. OO6
  2. U3CTqFPa09Twt
Product

monomeric RGD-modified lipid liposomes

Hydrodynamic diameter: 78.53 - 89.37 nm

Medium: water

Support: none

References

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