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pDNA-loaded methoxypoly(ethylene glycol)-block-poly(L-aspartic acid)-grafted polyethylenimine-functionalized superparamagnetic iron oxide nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

poly(iminoethylene)

polyethyleneimine polyaziridine PEI
Type Polymer
Formula
Role core
2

methoxypoly(ethylene glycol)-block-poly(L-aspartic acid)

mPEG-b-PAsp
Type Polymer
Formula
Role layer
3

tetramethylammonium 11-aminoundecanoate-coated Fe3O4 nanoparticles

Type Nano Material
Formula
Role fillers
4

pCMV-Luciferase2-mKate2

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability dependent on fetal bovine serum

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female Sprague-Dawley rat bone marrow mesenchymal stem cells

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Preparation

Method 1

Type: Physical formation
Source:
  1. WB6AW7zM46xwxmgR
Product

pDNA-loaded methoxypoly(ethylene glycol)-block-poly(L-aspartic acid)-grafted polyethylenimine-functionalized superparamagnetic iron oxide nanoparticles

Hydrodynamic diameter: ~ 133 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
  1. 1PwkKGpu4De7WeMq
Product

pDNA-loaded methoxypoly(ethylene glycol)-block-poly(L-aspartic acid)-grafted polyethylenimine-functionalized superparamagnetic iron oxide nanoparticles

Hydrodynamic diameter: ~ 71 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
  1. afTKEiZrQLVNKWmJ
Product

pDNA-loaded methoxypoly(ethylene glycol)-block-poly(L-aspartic acid)-grafted polyethylenimine-functionalized superparamagnetic iron oxide nanoparticles

Hydrodynamic diameter: ~ 122 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
  1. yYseVOPwNV0GUUBe
Product

pDNA-loaded methoxypoly(ethylene glycol)-block-poly(L-aspartic acid)-grafted polyethylenimine-functionalized superparamagnetic iron oxide nanoparticles

Hydrodynamic diameter: ~ 74 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
  1. LGKiBlMe9ZHEi9fE
Product

pDNA-loaded methoxypoly(ethylene glycol)-block-poly(L-aspartic acid)-grafted polyethylenimine-functionalized superparamagnetic iron oxide nanoparticles

Hydrodynamic diameter: ~ 112 nm

Medium/Support: none

References

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