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doxorubicin-loaded dexamethasone/folic acid/3-aminopropyltriethoxysilane/γ-3-mercaptopropyl triethoxysilane-modified mesoporous silica nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

mesoporous silica

Type Nano Material
Formula
Role core
2

γ-3-mercaptopropyl triethoxysilane

γ-3-mercaptopropyl triethoxysilane (3-mercaptopropyl)triethoxysilane 3-(mercaptopropyl)triethoxysilane 3-(triethoxysilyl)-1-propanethiol 3-mercaptopropyl triethoxysilane γ-mercaptopropyl triethoxysilane 3-Mercaptopropyltriethoxysilane 3-mercaptopropyltriethoxysilane mercaptopropyltriethoxysilane silane-SH 3-MPTES MPTES MPTS MPMS
Type Single Compound
Formula C9H22O3SSi
Role partial layer
3

(3-aminopropyl)-triethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety 3-aminopropyltriethoxysilane moiety γ-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role graft
4

folate acid

folic acid folate FOL FA
Type Single Compound
Formula C19H19N7O6
Role graft
5

(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

dexamethasone DEX DXM Dex
Type Single Compound
Formula C22H29FO5
Role graft
6

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on pH

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
HeLa cell line

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. VfworY5fBsiCJIYJJkWhSu7Y6FluO1Tafb
  2. a2pExnES
  3. q04D
Product

doxorubicin-loaded dexamethasone/folic acid/3-aminopropyltriethoxysilane/γ-3-mercaptopropyl triethoxysilane-modified mesoporous silica nanoparticles

References

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