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arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer

Based on

1 Articles
2014 Most recent source

Composition

1

G5 PAMAM dendrimer with ethylenediamine core and surface primary amine groups

generation 5 polyamidoamine dendrimer G5 PAMAM dendrimer
Type Polymer
Formula
Role raw materials
2

arginine moiety

Arg moiety
Type Single Compound
Formula -C6H13N4O
Role graft
3

phenylalanine moiety

Phe moiety
Type Single Compound
Formula -C9H10NO
Role graft
4

histidine moiety

His moiety
Type Single Compound
Formula -C6H8N3O
Role graft

Properties

Applications

Area Application Source
drug delivery

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Characterization

Method Source
nuclear magnetic resonance spectroscopy

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Biological effects

Biological system Test details Source
EGFP plasmid DNA

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • Boc-phenylalanine
  • Boc-His(Trt)-OH
  • Boc-Arg(Pbf)-OH
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  2. IXFyDIeo17kaPxeVA30huEbK4z
  3. TyUwboswe1Shm6rIBmsDfhVD5mj
  4. vBK
Product

arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • Boc-phenylalanine
  • Boc-His(Trt)-OH
  • Boc-Arg(Pbf)-OH
  1. gK2M3zQ58FFaB38TV0jJ8umz5DN3Gz
  2. ik3gJKObLZg7zWlvMDDyOluWPc
  3. 1tu0OiNMbiAwqDdMWz7SczA4KXe
  4. CVu
Product

arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • Boc-phenylalanine
  • Boc-His(Trt)-OH
  • Boc-Arg(Pbf)-OH
  1. QaIiA2SycAjw5a7V26febQRNFpsCiT
  2. 0g2vEKwctPVlvXtS5BcdPypzDz
  3. OqU7JdzYERe2jydV2eE8NatHxBv
  4. KiE
Product

arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • Boc-phenylalanine
  • Boc-His(Trt)-OH
  • Boc-Arg(Pbf)-OH
  1. dA3sClBBvQeHzh6xXj01ox1es3o9R6
  2. 7L2eSTfLkweaCoxdBsVbeiVNqy
  3. GQAuw01z5kErBst2tNNf1tQMIfw
  4. N5c
Product

arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • Boc-phenylalanine
  • Boc-His(Trt)-OH
  • Boc-Arg(Pbf)-OH
  1. jW3STBMQeJvVFTCRZVAJzuhSSpQhq0
  2. Ur6KmZ92EiSmqaNmaTdigEUATj
  3. 8PYdtuqcUKyTwntD4YfyJrP6Xyc
  4. G3I
Product

arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer

References

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