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coumarin-6-loaded Pep-1-conjugated PEG-PLGA nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

methoxyl poly(ethylene glycol)-co-poly(D,L-lactic-co-glycolic acid) copolymer

MePEG-PLGA
Type Polymer
Formula
Role raw materials
2

maleimidyl poly(ethylene glycol)-co-poly(D,L-lactic-co-glycolic acid) copolymer

MalePEG-PLGA
Type Polymer
Formula
Role raw materials
3

Pep-1

Type Biomolecule
Formula
Role loaded material
4

3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one

3-(2-benzothiazolyl)-N,N-diethylumbelliferylamine 3-(2-benzothiazolyl)-7-(diethylamino)coumarin coumarin 6 coumarin-6 6-coumarin C6 dye Cou6 C-6
Type Single Compound
Formula (CH3CH2)2NC8H4OCOC7H4NS
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
ICR mouse xenografted with rat glioma C6 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • maleimidyl poly(ethylene glycol)-co-poly(D,L-lactic-co-glycolic acid) copolymer
  1. Mg5eEP7QmOiZANaxqhTiIPrykh
Product

coumarin-6-loaded Pep-1-conjugated PEG-PLGA nanoparticles

Size: not specified

Medium/Support: none

References

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