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lipid-like nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

lipid mixture

Type Complex Compound
Formula
Role raw materials
2

mRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability

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Applications

Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57BL/6 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • lipid mixture
  • mRNA
Product

lipid-like nanoparticles

Hydrodynamic diameter: ~ 140 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • lipid mixture
  • mRNA
Product

lipid-like nanoparticles

Hydrodynamic diameter: 97 - 101 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • lipid mixture
  • mRNA
Product

lipid-like nanoparticles

Hydrodynamic diameter: ~ 101 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • lipid mixture
  • mRNA
Product

lipid-like nanoparticles

Hydrodynamic diameter: ~ 100 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • lipid mixture
  • mRNA
Product

lipid-like nanoparticles

Hydrodynamic diameter: ~ 88 nm

Medium/Support: none

References

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