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cisplatin-loaded lipid nanoparticles dispersion in water

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

water

Type Single Compound
Formula H2O
Role core
2

lipid mixture

Type Complex Compound
Formula
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
female Balb/c mice bearing 4T1 breast tumor

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy-poly(ethylene glycol)2000]
  • 1-palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine-cisplatin conjugate
See all (4)
  1. jNTr1hCBU4Yey8LDtlUd4Vg6cl
Product

cisplatin-loaded lipid nanoparticles dispersion in water

Diameter: ~ 98 nm

Hydrodynamic diameter: 104.4 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Product

cisplatin-loaded lipid nanoparticles dispersion in water

Diameter: ~ 98 nm

Medium/Support: none

References

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