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camptothecin/curcumin-loaded polymeric nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

poly(vinyl alcohol)

polyvinyl alcohol PVOH PVAI PVA
Type Polymer
Formula
Role layer
3

chitosan

Type Biomolecule
Formula
Role layer
4

(S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione

1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione (S)-(+)-camptothecin camptothecin CPT CMT CP
Type Single Compound
Formula C20H16N2O4
Role loaded material
5

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione 1,7-bis(4-hydroxy-3-methoxy phenyl)-1,6-heptadiene-3,5-diene 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione keto form curcumin diferuloylmethane curcumin CUR Cum Cur CCM CUM CU Cm CM
Type Single Compound
Formula C21H20O6
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  • poly(lactic-co-glycolic acid)
  • (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
  1. 5yFM6hYaO1lfzid1vNBt6tc7rGoiOyjsRZoknIvzdVTn
Product

camptothecin/curcumin-loaded polymeric nanoparticles

Hydrodynamic diameter: ~ 266 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  • poly(lactic-co-glycolic acid)
  • (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
  1. 4ZG5FBCbIvKElvDoN4L14plOlpUl9xdUbHuRhDPmI77R
Product

camptothecin/curcumin-loaded polymeric nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  • poly(lactic-co-glycolic acid)
  • (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
  1. JhTYQAVEd0QFB5p5DTjqxHYADxpMX5Txt9qRudEuoomK
Product

camptothecin/curcumin-loaded polymeric nanoparticles

Size: not specified

Medium/Support: none

References

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