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64Cu-loaded sorafenib functionalized melanin nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

polyethyleneglycol functionalized melanin nanoparticles

PEG-functionalized MNP
Type Nano Material
Formula
Role core
2

sorafenib tosylate

Type Single Compound
Formula C28H24ClF3N4O6S
Role layer
3

[64]copper(II) cation

[64Cu]copper(II) ion 64copper(II) ion copper-64 cation (64) copper ion copper(II) ion copper-64 ion 64Cu isotope 64copper ion copper ion 64Cu2+ ion 64Cu ion 64Cu(2+) 64Cu2+
Type Single Compound
Formula 64Cu2+
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability in phosphate-buffered saline

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
HepG2-tumor-bearing mice

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. u5IHFUInvqStmq7KfcLzbl5FSCUl
Product

64Cu-loaded sorafenib functionalized melanin nanoparticles

Diameter: ~ 60 nm

Medium/Support: none

References

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