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(Pt(IV))-conjugated cationic poly(amidoamine) dendrimer

Based on

1 Articles
2015 Most recent source

Composition

1

PAMAM dendrimer G4

Type Polymer
Formula
Role core
2

4-[(diaminodichlorohydroxyplatinio)oxy]-4-oxobutanoic acid

c,c,t-[Pt(NH3)2Cl2 (OOCCH2CH2COOH) (OH)] c,c,t-[Pt(NH3)2Cl2(OH)(O2CCH2CH2CO2H)] cisplatin prodrug Cis-Pt(NH3)2Cl2 DSP SCP
Type Single Compound
Formula C4H12Cl2N2O5Pt
Role layer

Properties

Applications

Characterization

Biological effects

Biological system Test details Source
H22 tumor-bearing mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 4-[(diaminodichlorohydroxyplatinio)oxy]-4-oxobutanoic acid
  • PAMAM dendrimer G4
  1. NIWhAGH8VzS0z388rvBgX1Kk5NIJjXlTYdajkwwyLblEnGxdraBAth7b1QV
  2. MSiYW0yEj0j6Xhx9suRB
  3. IWP5M3xswxLxnD9
  4. wOq8K15c
  5. BVk7
Product

(Pt(IV))-conjugated cationic poly(amidoamine) dendrimer

References

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