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Tf and Cy7-modified mesoporous SiO2-coated Fe3O4 nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

iron(II,III) oxide

magnetite
Type Single Compound
Formula Fe3O4
Role core
2

3-(trimethoxysilyl)propyl methacrylate moiety

3-(triethoxysilyl)propyl methacrylate moiety 3-methacryloxypropyltrimethoxy silane moiety 3-(methacryloxy)propylsilanetrioxy group 3-methacryloxypropyl silane moiety γ-methacryloxypropylsilane moiety TMSPMA moiety γ-MPS moiety MPTMS moiety MPTS moiety MPS moiety
Type Single Compound
Formula -C7H11O5Si-
Role graft
3

poly(tert-butyl acrylate)

PTBA
Type Polymer
Formula
Role layer
4

Vacuous

Type
Formula
Role layer
5

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role layer
6

(3-aminopropyl)trimethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety γ-aminopropyltriethoxysilane moiety 3-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role layer
7

cyanine 7 dye

cyanine 7 Cy7
Type Single Compound
Formula C37H45N2O2
Role layer
8

maleimide PEG N-hydroxysuccinimide ester

Mal-PEG-NHS
Type Polymer
Formula
Role layer
9

methoxy PEG succinimidyl carboxymethyl ester

PEG-NHS
Type Polymer
Formula
Role layer
10

transferrin

Tf-SH
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
magnetization

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
293T cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. bRpf3CGfXT7vEBz
Product

Tf and Cy7-modified mesoporous SiO2-coated Fe3O4 nanoparticles

Diameter: 450 - 550 nm

Pore size: 3.5 nm

Thickness: 70 - 90 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

Tf and Cy7-modified mesoporous SiO2-coated Fe3O4 nanoparticles

Diameter: 450 - 550 nm

Hydrodynamic diameter: ~ 550 nm

Pore size: 3.5 nm

Thickness: 70 - 90 nm

Medium: phosphate buffer solution

Support: none

References

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