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EGFR targeting affibody-conjugated cross-linked polyacrylate nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

amine-containing polyacrylate cross-linked polymer

Type Polymer
Formula
Role core
2

maleimide-PEG5k-carbonyl moiety

Type Polymer
Formula
Role layer
3

acetyl fragment

acetyl fragment acetyl group acetyl
Type Single Compound
Formula -C2H3O
Role layer
4

ZEGFR1907 affibody

Type Biomolecule
Formula
Role layer
5

methoxy-PEG1k-thiol

mPEG1k-SH
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
mouse bearing A431 tumor xenograft

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. eByK0i7nt738nL2VCMB0VCPPRW
Product

EGFR targeting affibody-conjugated cross-linked polyacrylate nanoparticles

Height: 55 nm

Hydrodynamic diameter: 164.3 - 167.5 nm

Length: 60 nm

Width: 55 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
  1. hrrXMm2ZG5rtPrOr9JFqRg71zE
Product

EGFR targeting affibody-conjugated cross-linked polyacrylate nanoparticles

Height: 55 nm

Hydrodynamic diameter: 158.4 - 168.0 nm

Length: 60 nm

Width: 55 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
  1. h1IxskeNyVtr2IDE99qLPgOgLJ
Product

EGFR targeting affibody-conjugated cross-linked polyacrylate nanoparticles

Height: 55 nm

Hydrodynamic diameter: 169.7 - 171.3 nm

Length: 60 nm

Width: 55 nm

Medium/Support: none

References

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