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anti-EpCAM antibody-conjugated QD630

Based on

1 Articles
2015 Most recent source

Composition

1

octadecylamine-coated CdSe/ZnS QD

QD630
Type Nano Material
Formula
Role core
2

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

DSPE-PEG2000
Type Polymer
Formula
Role layer
3

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (ammonium salt)

DSPE-PEG2000-amine
Type Polymer
Formula
Role layer
4

4-(N-maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester moiety

carbonyl-1,4-cyclohexanediylmethylene-2,5-dioxopyrrolidine-1,3-diyl unit 4-(N-maleimidomethyl)cyclohexane-1-carboxylic acid moiety sulfo-SMCC linker moiety sulfo-SMCC moiety sulfo-SMCC linker sulfo-SMCC unit SMCC moiety
Type Single Compound
Formula -C12H15NO3-
Role layer
5

SH-anti-EpCAM antibody

Type Biomolecule
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse with human breast carcinoma SK-Br3 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
Product

anti-EpCAM antibody-conjugated QD630

Hydrodynamic diameter: ~ 38 nm

Medium/Support: none

References

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