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pH-sensitive magnetic nanogrenades

Based on

1 Articles
2014 Most recent source

Composition

1

poly ((17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid/1-(3-aminopropyl)imidazole-aspartate monomer/dopamine-aspartate monomer/poly(ethylene glycol))

Type Polymer
Formula
Role raw materials
2

poly ((17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid/1-(3-aminopropyl)imidazole-aspartate monomer/3-phenyl-1-propylamine-aspartate monomer/poly(ethylene glycol))

Type Polymer
Formula
Role raw materials
3

extremely small iron oxide nanoparticles

ESION
Type Nano Material
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
longitudinal magnetic resonance relaxivity

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
HCT116 tumor-bearing mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

pH-sensitive magnetic nanogrenades

Hydrodynamic diameter: ~ 70 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • extremely small iron oxide nanoparticles
  • poly ((17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid/1-(3-aminopropyl)imidazole-aspartate monomer/3-phenyl-1-propylamine-aspartate monomer/poly(ethylene glycol))
  • poly ((17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid/1-(3-aminopropyl)imidazole-aspartate monomer/dopamine-aspartate monomer/poly(ethylene glycol))
  1. 2EuO
  2. 23wpjrxQaU
Product

pH-sensitive magnetic nanogrenades

Size: not specified

Medium/Support: none

References

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