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pH-sensitive theranostic nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

poly(lactic acid)-poly(ethylene glycol)-poly(L-lysine)-diethylenetriamine pentaacetic acid

PLA-PEG- PLL-DTPA
Type Polymer
Formula
Role raw materials
2

Poly-L-histidine - polyethylene glycol

PLH-PEG
Type Polymer
Formula
Role raw materials
3

Poly-L-histidine - polyethylene glycol- biotin

PLH-PEG-biotin
Type Polymer
Formula
Role raw materials
4

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role loaded material
5

gadolinium(III) chloride

gadolinium trichloride gadolinium chloride
Type Single Compound
Formula GdCl3
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug loading

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
Human hepatocellular carcinoma cells (HepG2)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  • poly(lactic acid)-poly(ethylene glycol)-poly(L-lysine)-diethylenetriamine pentaacetic acid
  • Poly-L-histidine - polyethylene glycol- biotin
See all (4)
  1. ylepLi8ind0OXaZaht3Su
Product

pH-sensitive theranostic nanoparticles

Diameter: 159.9 - 173.7 nm

Medium/Support: none

References

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