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DNA-loaded gemini surfactant-phospholipid nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

(2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphatidyl-ethanolamine 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleyl-sn-glycerophosphoethanolamine dioleoyl-phosphatidyl ethanolamine dioleoyl-phosphatidylethanol-amine dioleoylphosphatidylethanolamine DOPA DOPE
Type Single Compound
Formula C41H78NO8P
Role layer
3

pCMV-tdTomato/gemini surfactant 12-7NH-12

PG
Type Complex Compound
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
drug delivery

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Characterization

Biological effects

Biological system Test details Source
retinal ganglion RGC-5 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • pCMV-tdTomato
  • dodecyl(3-{[3-(dodecyldimethylazaniumyl)propyl]amino}propyl)dimethylazanium dibromide
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Product

DNA-loaded gemini surfactant-phospholipid nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  • water
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  2. srX6
Product

DNA-loaded gemini surfactant-phospholipid nanoparticles

Method 3

Type: Physical formation
Source:
Product

DNA-loaded gemini surfactant-phospholipid nanoparticles

Method 4

Type: Physical formation
Source:
Starting materials
  • pCMV-tdTomato
  • dodecyl(3-{[3-(dodecyldimethylazaniumyl)propyl]amino}propyl)dimethylazanium dibromide
  1. Vz4S5hfzRF440Z18
  2. Xnknt7Wg2c38BJWU
  3. zgQ3HN
Product

DNA-loaded gemini surfactant-phospholipid nanoparticles

Method 5

Type: Physical formation
Source:
Product

DNA-loaded gemini surfactant-phospholipid nanoparticles

References

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