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Docetaxel-loaded FA-PEG-b-PLGA/TPGS-PLGA nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

FA-PEG-b-PLGA/TPGS-PLGA

Type Complex Compound
Formula
Role carriers
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
human breast adenocarcinoma MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • folic acid-polyethylene glycol-poly(lactic-co-glycolic acid)
  • TPGS-PLGA
  1. 69vkoAyB9RQ7YYPn
  2. rMWn0ZddK
  3. 61az3FzLCD
Product

Docetaxel-loaded FA-PEG-b-PLGA/TPGS-PLGA nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • folic acid-polyethylene glycol-poly(lactic-co-glycolic acid)
  • TPGS-PLGA
  1. StK5QMkWL1lfkPQO
  2. E9mig29sL
  3. uVYBNym5i9
Product

Docetaxel-loaded FA-PEG-b-PLGA/TPGS-PLGA nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • folic acid-polyethylene glycol-poly(lactic-co-glycolic acid)
  • TPGS-PLGA
  1. Hd2wB6GvYJS2QxCF
  2. 71JzXboVY
  3. 53I6PVGCOt
Product

Docetaxel-loaded FA-PEG-b-PLGA/TPGS-PLGA nanoparticles

References

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