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all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(ethylene glycol)-block-polylactide

PEG-b-PLA
Type Polymer
Formula
Role raw materials
2

all-trans-retinoic acid/doxorubicin mixture

ATRA/DOX mixture
Type Complex Compound
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cancer stem cell-enriched MDA-MB-231 mammosphere cell line

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • all-trans-retinoic acid
  • poly(ethylene glycol)-block-polylactide
  • adriblastin
  1. laukW57xiG5jzTJP7Dskx48zdGhFgJPfbbMKzaJr
Product

all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Hydrodynamic diameter: 146.99 - 149.25 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • all-trans-retinoic acid
  • poly(ethylene glycol)-block-polylactide
  • adriblastin
  1. bejhS7SmZ8yHcxpKYqlqJgO6DgcrZszd3eUmrpkG
Product

all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Hydrodynamic diameter: 144.02 - 146.26 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • all-trans-retinoic acid
  • poly(ethylene glycol)-block-polylactide
  • adriblastin
  1. F0MswD4NvDHrETx9Uue34aX2dKsEui59rQCLjb0W
Product

all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Hydrodynamic diameter: 137.98 - 142.34 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • all-trans-retinoic acid
  • poly(ethylene glycol)-block-polylactide
  • adriblastin
  1. qVDaxyMJVjcKgQo3QOPdJWUmiQowEwDJlCcFFEq8
Product

all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Hydrodynamic diameter: 140.26 - 146.38 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • all-trans-retinoic acid
  • poly(ethylene glycol)-block-polylactide
  • adriblastin
  1. rtRzbDxq5qSiijbv3xVYH7ILEV7tZVgMPwpyxKU8
Product

all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Hydrodynamic diameter: 139.44 - 143.40 nm

Medium: water

Support: none

References

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