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all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(ethylene glycol)-block-polylactide

PEG-b-PLA
Type Polymer
Formula
Role raw materials
2

all-trans-retinoic acid/doxorubicin mixture

ATRA/DOX mixture
Type Complex Compound
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cancer stem cell-enriched MDA-MB-231 mammosphere cell line

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Preparation

Method 1

Type: Physical formation
Source:
Product

all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Hydrodynamic diameter: 143.03 - 149.97 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • all-trans retinoic acid
  • poly(ethylene glycol)-block-polylactide
  • adriblastin
  1. zspQlhyNTXUXt5McuZdYeuS9O7HHqDHJ2WV2XApY
Product

all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Hydrodynamic diameter: 137.98 - 142.34 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • all-trans retinoic acid
  • poly(ethylene glycol)-block-polylactide
  • adriblastin
  1. 3nqQqW2BZPoQ05nlkH8wEDyL8lkY20uZacxKqj3j
Product

all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Hydrodynamic diameter: 146.99 - 149.25 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • all-trans retinoic acid
  • poly(ethylene glycol)-block-polylactide
  • adriblastin
  1. SLzWTAnbSpmwDELuQLFe6WHZdY8WlolFw7jLIeee
Product

all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Hydrodynamic diameter: 144.02 - 146.26 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • all-trans retinoic acid
  • poly(ethylene glycol)-block-polylactide
  • adriblastin
  1. BS6qRWpZf4C7KpzAMDG0MtSqJ14sleskGg4xMyhu
Product

all-trans-retinoic acid/doxorubicin-loaded poly(ethylene glycol)-block-polylactide nanoparticles

Hydrodynamic diameter: 140.26 - 146.38 nm

Medium: water

Support: none

References

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