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WGA-functionalized itraconazole nanocrystals with cross-linked PAA-b-PMA cage

Based on

1 Articles
2015 Most recent source

Composition

1

cis-2-sec-butyl-4-[4-(4-{4-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4- ylmethoxy]phenyl}piperazin-1-yl)phenyl]-2,4-dihydro-1,2,4-triazol-3-one

itraconazole
Type Single Compound
Formula C35H38Cl2N8O4
Role core
2

2,2'-(ethylenedioxy)bis(ethylamine)-crosslinked poly(acrylic acid)-b-poly(methyl acrylate)

2,2'-(ethylenedioxy)bis(ethylamine)-crosslinked PAA-b-PMA
Type Polymer
Formula
Role layer
3

wheat germ agglutinin

WGA
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human epithelial colorectal adenocarcinoma Caco-2 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. EQxroPCD0pzoDKCm
  2. TfD6twm0
  3. SG9D
Product

WGA-functionalized itraconazole nanocrystals with cross-linked PAA-b-PMA cage

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

WGA-functionalized itraconazole nanocrystals with cross-linked PAA-b-PMA cage

Size: 238 - 248 nm

Medium: water

Support: none

References

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