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DNA-functionalized liposomal spherical nucleic acid nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

HEPES buffer

Type Complex Compound
Formula
Role core
2

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

Δ9-cis-1,2-dioleoyl-sn-glycero-3-phosphocholine 1,2-dioleoyl- sn-glycero-3-phosphatidylcholine 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine 1,2-dioctanoyl-sn-glycero-3-phosphocholine 1,2- dioleoyl-sn-glycero-3-phosphocholine 1,2-dioleoyl-sn-glycero-3- phosphocholine 1,2-dioleoyl-sn-glycero-3-phosphocholine Δ9-cis-sn-glycero-3-phosphocholine dioleoyl-phosphatidyl choline dioleoylphosphatidylcholine dioleoylphosphocholine 18:1 (Δ9-cis) PC 18:1(cis) PC DC18:1PC DOPC PC
Type Single Compound
Formula C44H84NO8P
Role layer
3

5'-Cy5-T25-tocopherol-3'

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability dependent on FBS presence; DNAse I presence

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human ovarian adenocarcinoma SKOV-3 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. N6xbJn4
  2. xLBsOjsz
Product

DNA-functionalized liposomal spherical nucleic acid nanoparticles

Hydrodynamic diameter: 46 nm

Medium: HEPES buffer

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. QbXxAqH
  2. pkURDmif
Product

DNA-functionalized liposomal spherical nucleic acid nanoparticles

Diameter: 18 - 32 nm

Thickness: ~ 5 nm

Medium/Support: none

References

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