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M-MSN_siRNA@PEI-PEG-KALA delivery vehicles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

magnetic mesoporous silica nanoparticles

M-MSN
Type Nano Material
Formula
Role core
2

siRNA

Type Biomolecule
Formula
Role loaded material
3

poly(iminoethylene)

polyethyleneimine polyaziridine PEI
Type Polymer
Formula
Role layer
4

PEG-KALA conjugate

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human alveolar basal epithelial adenocarcinomic A549 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • KALA peptide
  • N-hydroxy-succinimide-polyethylene glycol-maleimide
  1. qdiMSiYi5emmKddMR0TZ0o
  2. 0CaqU
Product

M-MSN_siRNA@PEI-PEG-KALA delivery vehicles

Size: ~ 50 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

M-MSN_siRNA@PEI-PEG-KALA delivery vehicles

Hydrodynamic diameter: 153 - 155 nm

Medium: DLS medium

Support: none

References

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