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doxorubicin-loaded redox-triggered-hollow mesoporous silica nanoreservoirs

Based on

1 Articles
2014 Most recent source

Composition

1

Vacuous

Type
Formula
Role core
2

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role layer
3

(3-mercaptopropyl)triethoxysilane moiety

3-mercaptopropyltrimethoxy silane moiety (1-mercaptopropyl)silanetriyl group 3-mercaptopropyl silane moiety 3-mercaptopropylsilyl fragment 3-mercaptopropylsilyl MPTMS moiety MPTS moiety MPS moiety
Type Single Compound
Formula -C3H7SSi-
Role layer
4

3-mercaptopropionic acid

mercaptopropionic acid 3-MPA MPA
Type Single Compound
Formula C3H6O2S
Role layer
5

1-amino-adamantane

1-adamantanamine 1-adamantylamine amantadine
Type Single Compound
Formula C10H17N
Role layer
6

β-cyclodextrin-lactobionic acid

β-CD-LA
Type Single Compound
Formula C56H96N2O46
Role layer
7

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on release buffer

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
thermogravimetric analysis

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Biological effects

Biological system Test details Nanomaterial Variant Source
HepG2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. SqXnO
Product

doxorubicin-loaded redox-triggered-hollow mesoporous silica nanoreservoirs

Diameter: 125 - 175 nm

Thickness: 17 - 23 nm

Medium/Support: none

References

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