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docetaxel-loaded TOS-grafted hyaluronic acid nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

TOS-grafted hyaluronic acid

HATS
Type Biomolecule
Formula
Role raw materials
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse with human prostate cancer PC-3 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • TOS-grafted hyaluronic acid
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. CRdseh1qn0gcm4aZyFHT0TVcr0rm
  2. amqA5pycAt
  3. NqNHXThxgiOOkp
Product

docetaxel-loaded TOS-grafted hyaluronic acid nanoparticles

Hydrodynamic diameter: 117.2 - 123.4 nm

Medium: DLS medium

Support: none

References

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