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Fe3O4-bLf-encapsulated locked nucleic acid modified aptamer-decorated alginate-enclosed chitosan-coated calcium phosphate nanocarriers

Based on

1 Articles
2015 Most recent source

Composition

1

calcium orthophosphate

β-tricalcium phosphate tricalcium phosphate calcium phosphate β-TCP CaPh CaP TCP CP
Type Single Compound
Formula Ca3(PO4)2
Role core
2

chitosan

Type Biomolecule
Formula
Role layer
3

Fe3O4-saturated bovine lactoferrin

Fe3O4-bLf complex Fe3O4-bLf
Type Nano Material
Formula
Role loaded material
4

locked nucleic acid modified aptamer targeting epithelial cell adhesion molecule

LNA EpCAM LNA Ep
Type Biomolecule
Formula
Role loaded material
5

locked nucleic acid modified aptamer targeting nucleolin

LNA Nucleolin LNA Nu
Type Biomolecule
Formula
Role loaded material
6

Ca/alginate

Type Biomolecule
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
mouse with colon cancer stem Caco-2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

Fe3O4-bLf-encapsulated locked nucleic acid modified aptamer-decorated alginate-enclosed chitosan-coated calcium phosphate nanocarriers

Hydrodynamic diameter: 250 - 300 nm

Medium: DLS medium

Support: none

Method 2

Type: Chemical synthesis
Source:
  1. KQil5NwD
Product

Fe3O4-bLf-encapsulated locked nucleic acid modified aptamer-decorated alginate-enclosed chitosan-coated calcium phosphate nanocarriers

Size: not specified

Medium/Support: none

References

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