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poly(D-α-tocopheryl polyethylene glycol 1000-2,2-bis(acryloyloxymethyl)propionate-co-N,N'-bis(acryloyl)cystamine-co-1,6-hexanediol diacrylate-co-piperazine) nanoparticles in phosphate-buffered saline (pH 6.5)

Based on

1 Articles
2015 Most recent source

Composition

1

poly(D-α-tocopheryl polyethylene glycol 1000-2,2-bis(acryloyloxymethyl)propionate-co-N,N'-bis(acryloyl)cystamine-co-1,6-hexanediol diacrylate-co-piperazine)

TPGS-SS-PBAE TPSS
Type Polymer
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
base dissociation constant

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human hepatocellular carcinoma HepG2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(D-α-tocopheryl polyethylene glycol 1000-2,2-bis(acryloyloxymethyl)propionate-co-N,N'-bis(acryloyl)cystamine-co-1,6-hexanediol diacrylate-co-piperazine)
  1. Ockbeux26NcbpJJm
Product

poly(D-α-tocopheryl polyethylene glycol 1000-2,2-bis(acryloyloxymethyl)propionate-co-N,N'-bis(acryloyl)cystamine-co-1,6-hexanediol diacrylate-co-piperazine) nanoparticles in phosphate-buffered saline (pH 6.5)

Hydrodynamic diameter: 87.1 - 107.5 nm

Medium: phosphate-buffered saline

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(D-α-tocopheryl polyethylene glycol 1000-2,2-bis(acryloyloxymethyl)propionate-co-N,N'-bis(acryloyl)cystamine-co-1,6-hexanediol diacrylate-co-piperazine)
  1. 3PsREo6ZIitQq4NI
Product

poly(D-α-tocopheryl polyethylene glycol 1000-2,2-bis(acryloyloxymethyl)propionate-co-N,N'-bis(acryloyl)cystamine-co-1,6-hexanediol diacrylate-co-piperazine) nanoparticles in phosphate-buffered saline (pH 6.5)

Hydrodynamic diameter: 65.2 - 91.6 nm

Medium: phosphate-buffered saline

Support: none

Method 3

Type: Physical formation
Source:
Product

poly(D-α-tocopheryl polyethylene glycol 1000-2,2-bis(acryloyloxymethyl)propionate-co-N,N'-bis(acryloyl)cystamine-co-1,6-hexanediol diacrylate-co-piperazine) nanoparticles in phosphate-buffered saline (pH 6.5)

Hydrodynamic diameter: 237.9 - 261.1 nm

Medium: phosphate-buffered saline with glutathione

Support: none

Method 4

Type: Physical formation
Source:
  1. drEcNH
Product

poly(D-α-tocopheryl polyethylene glycol 1000-2,2-bis(acryloyloxymethyl)propionate-co-N,N'-bis(acryloyl)cystamine-co-1,6-hexanediol diacrylate-co-piperazine) nanoparticles in phosphate-buffered saline (pH 6.5)

Hydrodynamic diameter: 113.4 - 123.4 nm

Medium: phosphate-buffered saline

Support: none

Method 5

Type: Physical formation
Source:
Product

poly(D-α-tocopheryl polyethylene glycol 1000-2,2-bis(acryloyloxymethyl)propionate-co-N,N'-bis(acryloyl)cystamine-co-1,6-hexanediol diacrylate-co-piperazine) nanoparticles in phosphate-buffered saline (pH 6.5)

Hydrodynamic diameter: 248.9 - 263.3 nm

Medium: phosphate-buffered saline with glutathione

Support: none

References

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