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LHRH peptide/DBCO-PEG4-NHS ester-poly (acrylamide-co-N-azidodeca-(ethylene glycol)ethylacrylamide-co-N,N-bis(acryloyl)cystamine)-covered-tumor-targeting p53 protein nanocapsules

Based on

1 Articles
2014 Most recent source

Composition

1

tumor-selective p53

mutant S121F
Type Biomolecule
Formula
Role core
2

poly (acrylamide-co-N-azidodeca-(ethylene glycol)ethylacrylamide-co-N,N-methylenebis(acrylamide))

Type Polymer
Formula
Role layer
3

dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester

Type Single Compound
Formula C34H39N3O10
Role graft
4

LHRH peptide

Type Biomolecule
Formula
Role graft

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
human foreskin fibroblasts cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • prop-2-enamide
  • N-azidodeca-(ethylene glycol)ethylacrylamide
  • N,N-bis(prop-2-enamidyl)cystamine
See all (4)
  1. 8KpxCTuLydGNApiTqGgsdiu043LMB2Q3vFivscQ6e1e0WZfqOI1R5xdry8hrvAdA9JJXluY7
Product

LHRH peptide/DBCO-PEG4-NHS ester-poly (acrylamide-co-N-azidodeca-(ethylene glycol)ethylacrylamide-co-N,N-bis(acryloyl)cystamine)-covered-tumor-targeting p53 protein nanocapsules

Size: not specified

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • prop-2-enamide
  • N-azidodeca-(ethylene glycol)ethylacrylamide
  • tumor-selective p53
See all (4)
  1. BgzxGQbp6WFyklcOF45s2udiZ4UATsYrZKGdyAhUDhma27nnOARFC2M3Ylfe9FRr87kdh7gV
Product

LHRH peptide/DBCO-PEG4-NHS ester-poly (acrylamide-co-N-azidodeca-(ethylene glycol)ethylacrylamide-co-N,N-bis(acryloyl)cystamine)-covered-tumor-targeting p53 protein nanocapsules

Size: not specified

Medium/Support: none

References

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