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TNF-α siRNA-loaded mannose-modified trimethyl chitosan-cysteine conjugate nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

cross-linked mannose-modified trimethyl chitosan-cysteine conjugate

cross-linked MTC conjugate
Type Biomolecule
Formula
Role raw materials
2

2'-O-methyl-modified TNF-α-specific siRNA duplex

tumor necrosis factor-alpha siRNA TNF-α siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source

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Applications

Area Application Source

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Characterization

Method Source

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Biological effects

Biological system Test details Source

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • mannose-modified trimethyl chitosan-cysteine conjugate
  • 2'-O-methyl-modified TNF-α-specific siRNA duplex
  • pentasodium tripolyphosphate anhydrous
  1. 8uiK9mlIwqBdAMFxw
  2. 6evJs
Product

TNF-α siRNA-loaded mannose-modified trimethyl chitosan-cysteine conjugate nanoparticles

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • mannose-modified trimethyl chitosan-cysteine conjugate
  • 2'-O-methyl-modified TNF-α-specific siRNA duplex
  • pentasodium tripolyphosphate anhydrous
  1. 2bJLSfW9jSMLpcS0Q
  2. L6nqU
Product

TNF-α siRNA-loaded mannose-modified trimethyl chitosan-cysteine conjugate nanoparticles

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • mannose-modified trimethyl chitosan-cysteine conjugate
  • 2'-O-methyl-modified TNF-α-specific siRNA duplex
  • pentasodium tripolyphosphate anhydrous
  1. LJ5m1RLq2JqE7dofB
  2. ZBVLj
Product

TNF-α siRNA-loaded mannose-modified trimethyl chitosan-cysteine conjugate nanoparticles

References

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