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dextran-DOX conjugate micelles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role core
2

dextran

Dex
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release amount

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
H22 hepatoma-xenografted male and female Kunming mouse

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Preparation

Method 1

Type: Physical formation
Source:
  1. YwV35aGYwveOwl3or5gyCWRF1
Product

dextran-DOX conjugate micelles

Diameter: ~ 89 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • doxorubicin hydrogen chloride
  • dextran
  • sodium cyanoborohydride
  1. jBx7X8GBEYfVde8NeFJsBU99iO
  2. JwasJa
  3. wtkcS
  4. lhae
  5. yvM9ZSZ0BYF
Product

dextran-DOX conjugate micelles

Hydrodynamic diameter: 60 - 136 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
  1. KXVXEvTytnNRgAQVmzyw9qF5x
Product

dextran-DOX conjugate micelles

Diameter: ~ 93 nm

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • doxorubicin hydrogen chloride
  • dextran
  1. s7qKyLC4ued4yImWwSwGHVrXmh
  2. tMFV1K
  3. zid3r
  4. BiKd
  5. 1Dd5mLjZq0D
Product

dextran-DOX conjugate micelles

Hydrodynamic diameter: 62 - 118 nm

Medium: phosphate buffer solution

Support: none

References

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