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DTX-loaded DSPE-PEG2000/TGPS/DSPE-PEG2000-folate micelles

Based on

1 Articles
2015 Most recent source

Composition

1

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role core
2

DSPE-PEG2000/TGPS/DSPE-PEG2000-folate

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female Balb/c nude mouse implanted with multidrug resistant human mouth epidermoid carcinoma KBv cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol 1000 succinate
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy-poly(ethylene glycol)2000]
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
See all (4)
  1. fgSfRRObrlPlyDtLIE1VPhp
Product

DTX-loaded DSPE-PEG2000/TGPS/DSPE-PEG2000-folate micelles

Hydrodynamic diameter: 17.68 - 19.56 nm

Medium/Support: none

References

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