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doxorubicin hydrochloride-encapsulated poly(methoxy-poly(ethylene glycol)/ethyl-p-aminobenzoate)phosphazene nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

water

Type Single Compound
Formula H2O
Role core
2

poly(methoxy-poly(ethylene glycol)/ethyl-p-aminobenzoate)phosphazene

PEP
Type Polymer
Formula
Role layer
3

doxorubicin hydrogen chloride

doxorubicin hydrochloride adriblastin hydrochloride adriamycin hydrochloride doxorubicin hydrochoride adriblastin HCl salt adriamycin HCl salt DOX hydrochloride DXR hydrochloride doxorubicin HCl Dox HCl Dox*HCl DOX*HCl DOX-HCl DOX·HCl DXR HCl DXR*HCl DOXS
Type Single Compound
Formula C27H30ClNO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
adriamycin resistant human breast carcinoma cell line (MCF-7/Adr)

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • hexachlorocyclotriphosphazene
  1. 0yJWSMfE6I03Ozanx
Product

doxorubicin hydrochloride-encapsulated poly(methoxy-poly(ethylene glycol)/ethyl-p-aminobenzoate)phosphazene nanoparticles

Diameter: 44.47 - 72.71 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • hexachlorocyclotriphosphazene
  1. lcktRGQ2jogNXPI0u
Product

doxorubicin hydrochloride-encapsulated poly(methoxy-poly(ethylene glycol)/ethyl-p-aminobenzoate)phosphazene nanoparticles

Diameter: 86.90 - 90.52 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • hexachlorocyclotriphosphazene
  1. hCJOk2ZYLUYyjKTPH
Product

doxorubicin hydrochloride-encapsulated poly(methoxy-poly(ethylene glycol)/ethyl-p-aminobenzoate)phosphazene nanoparticles

Diameter: 45.45 - 60.97 nm

Medium/Support: none

References

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